1

LncRNA HOTTIP modulated by Hedgehog signaling drives colorectal cancer progression by promoting HUWE1-mediated ubiquitin‒proteasome degradation of p53

Cell death & disease

9.6

罗时文

2025 Jul 7

2

Natural Product Auraptene Targets SLC7A11 for Degradation
and Induces Hepatocellular Carcinoma Ferroptosis

Antioxidants

6.6

边学利

2024/8/2029

3

Structural mechanism of human HCN1 hyperpolarization-activated channel inhibition by ivabradine.

Journal of Biological Chemistry

3.9

张进

2024.9.20

4

Cryo-EM Structure and Biochemical Analysis of the Human Chemokine Receptor CCR8.

Biochemistry

3

张进

2024.8.6

5

METTL3 restricts RIPK1-dependent cell death via the ATF3-cFLIP axis in the intestinal epithelium

cell regeneration

4.7

陈晔光

2024.8.2

6

Inhibition of XPR1-dependent phosphate efflux induces irreversible mitochondrial dysfunction: A potential molecular target therapy for hepatocellular carcinoma

Molecular Carcinogenesis

3.2

唐群

2024.8.18

7

Structural analysis of the human C5a-C5aR1 complex using cryo-electron microscopy

Journal of Structural Biology

2.7

张进

2024.8.15

8

Building consensus on the application of organoid-based drug sensitivity testing in cancer precision medicine and drug development

Theranostics

13.3

陈晔光

2024.5.27

9

New progress in roles of TGF-β signaling crosstalks in cellular functions, immunity and diseases

cell regeneration

4.7

陈晔光

2024.5.23

10

A growth factor-reduced culture system for colorectal cancer organoids

cancer letters

10.1

陈晔光

2024.4.28

11

Cryo-EM structure of human HCN3 channel and its regulation by cAMP.

Journal of Biological Chemistry

3.9

张进

2024.4.16

12

Interactions between MDSCs and the Autonomic Nervous System: Opportunities and Challenges in Cancer Neuroscience.

Cancer Immunology Research

8.2

邓欢

2024.3.2

13

TGFβ family signaling in human stem cell self-renewal and differentiation

Cell Regeneration

4.7

张龙，任江

2024.12.28

14

Standard: Human gastric cancer organoids

cell regeneration

4.7

陈晔光

2024.12.27

15

Identification of Brain Cell Type-Specific Therapeutic Targets for Glioma From Genetics

CNS NEUROSCIENCE & THERAPEUTICS

5

祝新根

2024.12.01

16

Iberverin Downregulates GPX4 and SLC7A11 to Induce
Ferroptotic Cell Death in Hepatocellular Carcinoma Cells

Biomolecules

4.8

边学利

2024.11.5

17

Engineered Macrophage Exosomes Deliver Drug-Targeted Therapy for Breast Cancer

WIRES NANOMED NANOBI

8.2

熊丽霞

2024.11.19

18

Identification of feature genes in intestinal epithelial cell types

cell regeneration

4.7

陈晔光

2024.11.15

19

MDH2 Promotes Hepatocellular Carcinoma Growth Through
Ferroptosis Evasion via Stabilizing GPX4

International Journal of Molecular Sciences

4.9

边学利

2024.10.29

20

Interplay between acetylation and ubiquitination controls PSAT1 protein stability in lung adenocarcinoma

communications biology

5.2

王建斌

2024.10.21

21

Breast cancer-derived CAV1 promotes lung metastasis by regulating integrin α6β4 and the recruitment and polarization of tumor-associated neutrophils

Int J Biol Sci

10

熊丽霞

2024.10.15

22

Homeobox B9 promotes the invasion and metastasis of hepatocellular carcinoma cells via the EZH2-MIR203A-SNAI2 axis

Journal of Translational Medicine

7.5

邵江华

2024.10.10

23

The significance of HAUS1 and its relationship with immune microenvironment in hepatocellular carcinoma

Journal of cancer

3.2

王恺

2024.1.16

24

Inhibitor of differentiation 3 confers the robust anti-tumor activity of Kupffer cells

MedComm

10.7

张龙，任江

2024.08.08

25

Endosome-microautophagy targeting chimera (eMIATAC) for targeted proteins degradation and enhance CAR-T cell anti-tumor therapy

Theranostics

13.3

祝新根

2024.07.22

26

Phospholipids with two polyunsaturated fatty acyl tails: an important driver of ferroptosis

MedComm

10.7

张龙

2024.06.25

27

Upregulation of CYR61 by TGF-β and YAP signaling exerts a counter-suppression of hepatocellular carcinoma

Journal of Biological Chemistry

3.9

严晓华

2024.03.21

28

Mi-2β promotes immune evasion in melanoma by activating EZH2 methylation Nat Commun

Nature Communications

15.7

崔儒涛

2024.03.09

29

The prognostic implications and tumor-suppressive functions of CYR61 in estrogen receptorpositive breast cancer.

Frontiers in Immunology

5.9

涂硕、严晓华

2024.02.08

30

Establishment of a hydrodynamic delivery system in ducks

Transgenic Research

2

张春波

2024.4

31

BMP suppresses Wnt signaling via the Bcl11b-regulated NuRD complex to maintain intestinal stem cells

EMBO Journal

8.3

陈晔光、李叶华

2024.12

32

In vivo and in vitro study on the regulatory mechanism of XiaoChaiHu decoction on PANoptosis in sepsis-induced cardiomyopathy

Journal of Ethnopharmacolog

5.4

刘丹

2024